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Intermediate Products List
| API | Intermediates | Structure | Cas No. | |
| Agomelatine | 1 ☆ | 2-(7-methoxy-3,4-dihydronaphthalen-1-yl)acetonitrile |  |
861960-34- 1 |
| 2 ☆ | 3,4-Dihydro-7-methoxy-1(2H)-naphthalenone |  |
6836-19-7 | |
| 3 ☆ | 4-(4-Methoxyphenyl)butanoic acid |  |
4521-28-2 | |
| 4 ☆ | 2-(7-methoxynaphthalen-1-yl)acetonitrile |  |
138113-08- 3 | |
| 5 | 7-Methoxy-1-naphthaleneacetic acid |  |
6836-22-2 | |
| 6 | 2-(7-methoxynaphthalen-1-yl)ethanamine |  |
138113-09- 4 | |
| 7 | 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride |  |
139525-77 -2 | |
| Asenapine maleate | 1 ☆ | 1-(2,5-dichlorophenyl)ethanone |
 |
2476-37-1 |
| 2 ☆ | 1-(5-chloro-2-phenoxyphenyl)ethanone |  |
70958-18-8 | |
| 3 ☆ | 2-(5-chloro-2-phenoxyphenyl)acetic acid |
 |
70958-20-2 | |
| 4 | 3-(5-chloro-2-phenoxyphenyl)-1-methylpyrrolidine-2,4-dione |
 |
1162120-35-5 | |
| 5 ☆ | methyl 2-(2-(5-chloro-2-phenoxyphenyl)-N-methylacetamido)acetate |  |
1180843-76-8 | |
| 6 | 2-(2-(4-chlorophenoxy)phenyl)acetic acid |  |
25563-04-6 | |
| 7 ☆ | 11-Chloro-2,3-dihydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one |  |
1012884-46-6 | |
| 8 | Trans(+/-)-11-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1one |
 |
129385-59-7 |
|
Bazedoxifene Acetate |
1 | 1-[2-[4-(Chloromethyl)phenoxy]ethyl]hexahydro-1H-azepine |  |
212771-30-7 |
| 2 | (4-(2-(azepan-1-yl)ethoxy)phenyl)Methanol |  |
223251-16-9 | |
| 3 | 3-Methyl-5-(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-1H-indole |  |
198479-63-9 | |
| 4 | 4-Benzyloxyaniline |  |
6373-46-2 | |
| 5 | 1-{2-[4-(Chloromethyl)phenoxy]ethyl}azepane hydrochloride (1:1) |  |
223251-25-0 | |
| Brinzolamide | 1 | 3-(bromoacetyl)-2-thiophenesulfonamide |  |
154127-28-3 |
| Citalopra | 1 | 5-Cyanophthalide |  |
82104-74-3 |
| Finasteride | 1 | 3-Oxo-4-aza-5-alpha-androstane-17-beta-carboxylic acid |  |
103335-55-3 |
| 2 | Dihydroproscar | 
| 98319-24-5 | |
Lenalidomide |
1 ☆ | benzyl 2,6-dioxopiperidin-3-ylcarbamate |  |
24666-55-5 |
| 2 ☆ | alpha-t-BOC-L-glutamine |  |
13726-85-7 | |
| 3 ☆ | methyl 2-(bromomethyl)-3-nitrobenzoate |  |
98475-07-1 | |
| 4 ☆ | 3-aminopiperidine-2,6-dione hydrochloride |  |
2686-86-4 /24666-56-6 |
|
| 5 ☆ | 3-(4-nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione |  |
827026-45-9 | |
| Palonosetron | 1 | (S)-(-)-3-Aminoquinuclidine dihydrochloride |  |
119904-90-4 |
| 2 | 5,6,7,8-tetrahydronaphthalene-1-carboxylic acid |  |
4242-18-6 | |
| 3 ☆ | (S)-N-(quinuclidin-3-yl)-5,6,7,8- tetrahydronaphthalene-1-carboxamide |  |
135729-78-1 | |
| 4 ☆ | (S)-2-(1-Azabicyclo[2.2.2]oct-3-yl)-2,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one |  |
135729-56 -5 | |
| 5 ☆ | (S,S)-Palonosetron |  |
135729-60-1 | |
| Sitagliptin monohydrate | 1 | 2,4,5-Trifluorophenylacetic acid | 
| 209995-38-0 |
| Vilazodone | 1 ☆ | 3-(4-chlorobutanoyl)-1H-indole-5-carbonitrile |  |
276863-95-7 |
| 2 | 3-(4-Chlorobutyl)indole-5-carbonitrile |  |
143612-79-7 | |
| 3 ☆ | 5-(1-piperazinyl)-2-Benzofurancarboxylic acid ethyl ester Monohydrochloride |  |
765935-67-9 | |
| 4 ☆ | ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate |  |
163521-20-8 | |
| 5 | 5-Piperazin-1-yl-1-benzofuran-2-carboxylic acid |  |
183288-47-3 | |
| 6 ☆ | Ethyl 5-nitrobenzofuran-2-carboxylate |  |
69404-00-8 | |
| 7 ☆ | ETHYL 5-AMINOBENZOFURAN-2-CARBOXYLATE |  |
174775-48-5 | |
| 8 ☆ | 5-amino-2-benzofurancarboxylic acid methyl ester |  |
1646-29-3 | |
| 9 | Bis(2-chloroethyl)amine hydrochloride |  |
821-48-7 | |
| Zafirlukast | 1 | Methyl-4-bromomethyl-3-methoxy benzoate |  |
70264-94-7 |
| 2 | 5-Nitroindole | 
| 6146-52-7 | |
☆ Other chemical intermediates |
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| Intermediates | Structure | Cas No. | ||
| 1 ☆ | 6-Bromonaphthalen-2-amine |  |
7499-66-3 | |
| 2 ☆ | 2-Bromo-6-fluoronaphthalene |  |
324-41-4 | |
| 3 | (S) -1-Amino-1,2,3,4-Tetrahydronaphthalene Tartarate |  |
114352-02-2 | |
| 4 | bis(trimethylsilyl)trifluoroacetamide |  |
25561-30-2 | |
| 5 | Dihydrofuran-3(2H)-one |  |
22929-52-8 | |
☆ Tinib Series |
||||
| Axitinib | 1 | 3-Iodo-6-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole |  |
886230-74-6 |
| 2 | 3-Iodo-6-nitroindazole |  |
70315-70-7 | |
| 3 | N-methyl-2-sulfanylbenzamide |  |
20054-45-9 | |
| Dasatinib | 1 | 2-Chloro-6-methylaniline |  |
87-63-8 |
| 2 | 3-ethoxyacryloyl chloride |  |
6191-99-7 | |
| 3 | Methyl 2-aminothiazole-5-carboxylate |  |
6633-61-0 | |
| 4 | Ethyl 2-aminothiazole-5-carboxylate |  |
32955-21-8 | |
| 5 | (E)-N-(2-Chloro-6-methylphenyl)-3-ethoxyacrylamide |  |
863127-76-8 | |
| 6 | 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide |  |
302964-24-5 | |
| 7 | N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide |  |
302964-08-5 | |
| 8 | 3-Butoxyacryloyl chloride |  |
75945-53-8 | |
| Lapatinib | 1 | 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde |  |
231278-84-5 |
| 2 | 2-Formylfuran-5-boronic acid |  |
27329-70-0 | |
☆ Strong products The products under valid patents will not be offered to the countries covered by the patents. |
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